I would like to thank Aiping Zhu, Tian-Sheng Lu, and Shuyu Hou from Medpace Bioanalytical Laboratories, for sharing their poster from ASMS 2024. "A Simple and Sensitive LC-MS/MS Method for Quantification of 7α-hydroxy-4-cholesten-3-one (C4) in Human Serum." I found the application particularly interesting as it shows how Pentafluorophenyl (PFP) HPLC...

I would like to thank Emily Crawford, et.al from the University of North Carolina Chapel Hill for sharing their poster from ASMS 2024 titled "Assessing Antidepressant Pharmaceuticals in the Environment through the Development of a Multidimensional Liquid Chromatography-Ion Mobility Spectrometry-Mass Spectrometry Library." Although we are...

The Chemical Evaluation Research Institute (CERI), manufacturer of the L-Column Series recently presented its poster at HPLC 2024 in Denver Colorado. The poster entitled "Unlocking the Potential of Basic Compounds Analysis Through pH Optimization Using a High Alkali-Resistant Column in RPLC Analysis" reveals the advantages...

Pittcon 2024: Conference & Expo showcasing the latest advancements in fluidic technology, refractive index detection, fluorescence detectors & more!The following shows the product experts preparing to present at Pittcon 2024 in San Diego, CA. Despite some audio challenges, the rehearsal provides some valuable insights focusing...

Trimethylsilyl reagents (TMS) have been widely used as end-capping reagents for silica-based reversed-phase LC packing. As a new concept, 1,2-bis(dimethylchlorosilyl)ethane, which was bonded to the methyl groups of two trimethylchlorosilane reagents, was thought to function as a denser end-capping reagent than trimethylchlorosilane. In this study,...

I want to thank Alexandra Izydorczak, Troy Wood and  Wilfrido Mojica for sharing their poster Metabolic Profiling of Cancer Biomarkers from Methanol Extracts from Pathology Specimens using LC-MS/MS from ASMS 2023. Although we are not related to this poster, other than receiving it, I found the chromatography and method interesting. The following...