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Trimethylsilyl reagents (TMS) have been widely used as end-capping reagents for silica-based reversed-phase LC packing. As a new concept, 1,2-bis(dimethylchlorosilyl)ethane, which was bonded to the methyl groups of two trimethylchlorosilane reagents, was thought to function as a denser end-capping reagent than trimethylchlorosilane. In this study,...
We have received inquiries for degassing in relation to Surface Plasmon Resonance (SPR). and most recently for the Nicoya OpenSPR benchtop SPR. I was curious to learn about the system so that we can provide better support. The following paper "Application of the Nicoya OpenSPR...
I want to thank Alexandra Izydorczak, Troy Wood and Wilfrido Mojica for sharing their poster Metabolic Profiling of Cancer Biomarkers from Methanol Extracts from Pathology Specimens using LC-MS/MS from ASMS 2023. Although we are not related to this poster, other than receiving it, I found the chromatography and method interesting. The following...
I would like to thank Katherine Nyarko, Kaitlyn Boozer, and C. Michael Greenlief for sharing their paper "Profiling of the Polyphenol Content of Honey from Different Geographical Origins in the United States" Although we are not related to this work, other than receiving it, I found the application particularly...
I would like to thank Hayley Herderschee, Ph.D. (c) for sharing her poster from HPLC 2022. Although we are not related to this poster, other than receiving it, I found the chromatography interesting. The poster is entitled "HPLC- and UHPLC-MS Analysis of Pharmaceutically Relevant Biomacromolecules on the Analytical and...
While reading Lab Manager I came across this article titled, "Is Outsourcing Calibration and Metrology Services Right for You?" by Roark Galloway of Full Spectrum Lab Services from CBRE. • Roark's article speaks about the post-pandemic landscape, laboratory managers are prioritizing operational efficiency. Whether in large or small labs, managing multiple...
Phenyl and biphenyl stationary phases in chromatography are explored.These phases exhibit dipole-dipole interactions, including π-π, CH-π, OH-π, NH-π, halogen-π, and lone pair electron-π interactions.The study focuses on the role of π-π and CH-π interactions in separating different compounds.Dinitrobenzene, trinitrobenzene, and sulfonamides are used to evaluate...
This poster introduces the Chromanik ArmorShell C18 Column and how it compares to other C18 Hybrid HPLC Columns. Trimethylsilyl reagents (TMS) have been commonly used to cap silica-based reversed-phase LC packing. However, difunctional silyl reagents like hexamethyl dichloro trisiloxane have been introduced to reduce residual silanol groups on...
We collaborate with a company that manufactures a life science (IVD) product utilizing single-use cartridges. During the manufacturing process, they face bubble formation in the cartridges, which can negatively impact the accuracy of their test results. To address this issue, the team responsible for instrument manufacturing...
ChromaNik Technologies’ New HPLC Products For 2023 SunShell Bio C18SunShell Bio C4SunShell Bio PhenylSunShell SFC 2-EPSunShell SFC DiolSunShell SFC SilicaSunShell HILIC DiolSunShell HILIC AmideSunShell HILIC SilicaSunShell Biphenyl 2.6 μmProminert Biphenyl 3.5 μmSunniest Biphenyl 5 μm ...
