Trimethylsilyl reagents (TMS) have been widely used as end-capping reagents for silica-based reversed-phase LC packing. As a new concept, 1,2-bis(dimethylchlorosilyl)ethane, which was bonded to the methyl groups of two trimethylchlorosilane reagents, was thought to function as a denser end-capping reagent than trimethylchlorosilane. In this study,...

Phenyl and biphenyl stationary phases in chromatography are explored.These phases exhibit dipole-dipole interactions, including π-π, CH-π, OH-π, NH-π, halogen-π, and lone pair electron-π interactions.The study focuses on the role of π-π and CH-π interactions in separating different compounds.Dinitrobenzene, trinitrobenzene, and sulfonamides are used to evaluate...

This poster introduces the Chromanik ArmorShell C18 Column and how it compares to other C18 Hybrid HPLC Columns. Trimethylsilyl reagents (TMS) have been commonly used to cap silica-based reversed-phase LC packing. However, difunctional silyl reagents like hexamethyl dichloro trisiloxane have been introduced to reduce residual silanol groups on...

We collaborate with a company that manufactures a life science (IVD) product utilizing single-use cartridges. During the manufacturing process, they face bubble formation in the cartridges, which can negatively impact the accuracy of their test results. To address this issue, the team responsible for instrument manufacturing...