I would like to thank Aiping Zhu, Tian-Sheng Lu, and Shuyu Hou from Medpace Bioanalytical Laboratories, for sharing their poster from ASMS 2024. "A Simple and Sensitive LC-MS/MS Method for Quantification of 7α-hydroxy-4-cholesten-3-one (C4) in Human Serum." I found the application particularly interesting as it shows how Pentafluorophenyl (PFP) HPLC...

I would like to thank Emily Crawford, et.al from the University of North Carolina Chapel Hill for sharing their poster from ASMS 2024 titled "Assessing Antidepressant Pharmaceuticals in the Environment through the Development of a Multidimensional Liquid Chromatography-Ion Mobility Spectrometry-Mass Spectrometry Library." Although we are...

Phenyl and biphenyl stationary phases in chromatography are explored.These phases exhibit dipole-dipole interactions, including π-π, CH-π, OH-π, NH-π, halogen-π, and lone pair electron-π interactions.The study focuses on the role of π-π and CH-π interactions in separating different compounds.Dinitrobenzene, trinitrobenzene, and sulfonamides are used to evaluate...

This poster introduces the Chromanik ArmorShell C18 Column and how it compares to other C18 Hybrid HPLC Columns.Trimethylsilyl reagents (TMS) have been commonly used to cap silica-based reversed-phase LC packing. However, difunctional silyl reagents like hexamethyl dichloro trisiloxane have been introduced to reduce residual silanol groups on...