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Curious if EME works for your compound? Use our convenient search tool to find out. Simply enter the name of your small organic molecule. If EME is compatible, we’ll show recommended extraction conditions along with application notes when available.
How does it work?
Two separate vials holding the sample solution and the acceptor solution.
The vials are separated by an organic solvent immobilized in the pores of a polymeric membrane, called the supported liquid membrane (SLM).
By applying an electric field across the membrane, charged analytes are transported by electrokinetic migration from the sample solution into the acceptor solution, while non-ionic analytes and ions of opposite charge are withheld in the sample solution.
You now have pure sample extract. Under optimized conditions, EME can provide very clean extracts with reduced matrix effects i.e. a complete discrimination of proteins and phospholipids, reducing downtime of your MS instruments. The extracts can be injected directly on LC-MS instruments using very short LC methods before MS.
What is Electromembrane Extraction (EME)?
Electromembrane Extraction (EME) is an advanced microextraction technique designed for preparing aqueous samples prior to analytical methods such as LC-MS, GC-MS, electrophoresis, and chromatography. It uses an electric field to selectively transfer charged analytes across a liquid membrane, offering high efficiency with minimal sample handling.
Why use Electromembrane Extraction (EME)?
EME provides rapid extractions, efficient sample clean-up and high selectivity for ionizable compounds from blood, other body fluids and environmental samples. The technique will be perfect for automation in laboratories.
Electromembrane Extraction (EME) is an advanced microextraction technique designed for preparing aqueous samples prior to analytical methods such as LC-MS, GC-MS, electrophoresis, and chromatography. It uses an electric field to selectively transfer charged analytes across a liquid membrane, offering high efficiency with minimal sample handling.
EME has the potential to become responsible for the paradigm shift because the technology provides:
Features:
Is Electromembrane Extraction (EME) Right for Your Analytes?
Find out here if EME is suitable for your analytes