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Impressive Extraction Efficiency of Biomaterials by Through Compression
Cryo-Press (Frozen Cell Crusher) freezes tissue that is difficult to crush, then degenerates with liquid nitrogen and crushes it. Analysis of biological substances such as: protein, DNA, and RNA extracted from tissues is necessary for research in many fields. Among these biological substances, enzymes and mRNAs are particularly vulnerable to heat. In the conventional pulverization method, heat is generated by crushing and the target substance is thermally denatured. If this process is hindered, the collection rate will be very low. Additionally, the conventional pulverization method did not satisfy the need to crush hard tissues such as: skin, hair, bone, and animal/plant fibers.
Cryo-Press was created to solve these problems. The cell (container) of the Cryo-Press is made of stainless steel and this cell is cooled with the sample in liquid nitrogen (about -180℃). Then the air compressor crushes the tissue and cell instantly.
Through instant pulverization, heat is minimized during crushing. As a result, this leads to a dramatic increase in the extraction-rate of living tissue. Compared with a rotary homogenizer, one is less likely to physically destroy the state of the target object by crushing with a hitting method. The crushing ability of the air compressor system is strong and effective.