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HPLC Columns
HPLC Columns (High-performance liquid chromatography), used in analytical chemistry, rely on a pump to push a sample mixture through a column containing an adsorbent material causing a separation of the mixture components as they flow out of the column. Our columns as well as the particle size of the packing material vary in size and are available for most applications.
Silica Columns– Porous
Precision-engineered porous silica HPLC columns for superior chromatographic separation.
Our fully porous silica columns deliver peak efficiency, selectivity, and reproducibility for pharmaceutical analysis, environmental testing, and life sciences research.
Why Choose Porous Silica Columns?
Larger surface area and deeper pore structure make them ideal for complex sample matrices, high-load applications, and methods requiring maximum retention and resolution.
Column Options
C18, RP-AQUA, C28, C30, Cyano, Phenyl, and Biphenyl are available across the ChromaNik Sunniest, Sunrise, and CERI L-column series.
Silica Columns – CoreShell
Polymer-based HPLC columns for separations beyond the limits of silica.
Stable across the full pH range, our polymeric columns offer unique selectivity for ion exchange, size exclusion, chiral separations, and applications where silica falls short.
Why Choose CoreShell Columns?
A solid silica core with a thin porous outer shell reduces band broadening and backpressure, ideal for faster run times and sharper peaks without upgrading your system.
Column Options
C18, C8, C4, Phenyl, Biphenyl, PFP, RP-AQUA, HILIC, and SFC phases available across the ChromaNik SunShell and SunArmor series.
Silica Gel- Hybrid
Fully porous ultra-hybrid silica HPLC columns engineered for unparalleled stability and performance.
Built on proprietary technologies, our hybrid silica columns integrate advanced silica surface treatment with innovative organosilica particle design — delivering durability and inertness that surpasses conventional C18 columns.
Why Choose Silica Gel Hybrid Columns?
Hybrid silica columns combine the best of inorganic silica and organic polymer structures, offering superior pH stability, lower adsorption of basic and chelating compounds, and longer column life, ideal for demanding applications where conventional silica falls short.
Column Options
SunBridge- C18 (1.8 µm, 3 µm, 5 µm) and PFP-R (3 µm) for extreme pH stability, ion-pair chromatography, and PFAS analysis.
Prominert- C18 and Biphenyl (3.5 µm) for superior inertness and peak symmetry in LC/MS and routine pharmaceutical analysis.
Silica Guard Columns/ Filters
Pre-column protection that extends analytical column life and maintains consistent performance.
Guard columns and filters intercept particulates and strongly retained compounds before they reach your analytical column, reducing downtime and protecting your investment.
Why Choose Guard Columns / Filters?
A simple, cost-effective way to significantly extend column lifespan and ensure reproducible results run after run.
Column Options
C18, C8, and RP-AQUA phases in both Porous (ChromaNik Sunniest, SunArmor, CERI L-column) and CoreShell (ChromaNik SunShell) configurations are available as cartridges, starter kits, and with holders.
Polymeric Columns
Polymer-based HPLC columns for separations beyond the limits of silica.
Stable across the full pH range, our polymeric columns offer unique selectivity for ion exchange, size exclusion, chiral separations, and applications where silica falls short.
Why Choose Guard Columns / Filters?
Full pH stability and broader application coverage ideal when silica-based columns can’t keep up.
Column Options
Amino Acids, Cation/Ion Exchange, Chiral, Reverse Phase, and Size Exclusion are available under the MCI Gel series by Mitsubishi Chemical.
U.S. Pharmacopeia (USP) Columns List
USP-compliant HPLC columns for pharmaceutical method development and quality control.
Our USP columns meet the strict packing requirements defined by the U.S. Pharmacopeia, ensuring your methods are validated, reproducible, and regulatory-ready.
Why Choose Guard Columns / Filters?
Guaranteed compliance with USP specifications simplifying method transfers, audits, and regulatory submissions across L1, L3, L7, L10, L11, L21, L25, L26, L32, L43, L62, and L68 categories.
Column Options
C18, C8, C4, C30, Cyano, Phenyl, Biphenyl, PFP, RP-AQUA, HILIC (Silica, Amide), Size Exclusion, Chiral, and Reverse Phase across ChromaNik Sunniest, SunShell, SunArmor, CERI L-column, and MCI Gel series.
SUMIKA Chiral Columns
Pioneer chiral HPLC columns for precise optical isomer separation.
The SUMICHIRAL OA series uses low molecular weight chiral selectors to deliver high-quality separation of enantiomers compatible with HPLC, LC-MS, and SFC systems.
Why Choose SUMIKA Chiral Columns?
Direct enantiomer separation with a large number of theoretical plates, elution order inversion capability, and broad compatibility with LC-MS and SFC workflows.
Column Options
Amide-Type, Urea-Type, Ligand Exchange-Type, Host-Guest-Type, and Protein-based across the SUMICHIRAL OA-2000 through OA-8000 series.