Classical Normal Phase – Bare (Unbonded) Silica

Normal phase HPLC applications suitable for separations of polar and basic organic compounds, such as vitamins and steroids, as well as pharmaceuticals. The rigid structure of the silica surface allows it to discern between molecules with different footprints that may have the same hydrophobicity. Isomers and related substances can be separated on unbonded silica under normal phase conditions.

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