100 angstrom, 120 angstrom, and 300 angstrom ultra-pure silica derivatized with C8 and end-capping offers an extensive range of hydrophobic separation power with high surface area coverage, in case less retention is required compared to a C18. Compounds elute faster, resulting in less time-consuming separations. The unique chemistry of bonded C8 ligands on ZEOsphere C8 phases provides exceptional performance for a variety of analytical and preparative applications.