Biotech Liquid Flowmeter Used to Obtain Real-time Tracing of Your Fluidic System. Eliminate Uncertainty.
Biotech Liquid Flow Meters
Continuous High Precision Flow Monitoring with the Biotech Liquid Flow Meters
Measuring of liquid flow rate has traditionally been slow and elaborative. Still today, volumetric flow meters are common despite their significant limitations. High-Resolution Flow Measurement (HRFM) has now been made easy, continuous, and integrated by the series of Biotech Liquid Flow Meters. With these devices, flow data is continuously and accurately recorded and stored in a computer application providing full flow control and documentation. The measurement principle of heat dispersion allows for unprecedented time resolution and provides new insights into flow variation and inconsistency. The internal flow cell has a minimal volume and the inline measurement is accomplished without any interference with the liquid or its flow path.
- Chromatography validation (IQ, OQ, PQ)
- Peristaltic pump monitoring and control
- Flow chemistry process control
- Process quality assurance and validation
Micro-flow meter
With a measuring range from 10 nL/min to 80 µL/min, and a 5 µL flow cell made of quartz glass and PEEK, this unit provides unprecedented insights into nano-fluidics.
HPLC flow meter
Optimised for flow rates from 1 µL/min to 5 mL/min, this flow meter fits all modern HPLC, UHPLC, and similar systems. It has a very robust flow sensor made of quartz glass and PEEK.
Prep flow meter
Ranging up to 40 mL/min with the same high precision, accuracy and time resolution as the smaller models, the Prep Flow Meter fills a role in scaling up to fully preparative systems
High flow meter
Based on the same technology, the High Flow Meter provides continuous recording of full-flow data up to 650 mL/min without sacrificing precision or accuracy.
Time-resolved flow measurement
The Biotech Liquid Flow Meters allow the user to select how to monitor the flow by simple adjustment of the sampling speed. This enables monitoring of the average flow rate or recording of the full flow profile including any pump pulsation on a previously unprecedented level. With this device, you might detect pulsations that can explain unexpected results and deviations.
Higher pulsation could indicate for example a leaking pump seal or malfunctioning check valve. This means the Biotech Liquid Flow Meters will be a diagnostic tool for your fluidic system. All data is continuously saved in the computer application via the USB connection which also powers the unit.
Application examples
Calibration and pump validation protocol
Every flow meter comes delivered with a Certificate of Conformity verified by a 4+1 point test routine. For regulated industries, we offer a traceable 10-point calibration with a Certificate and a Pump Validation Protocol. This provides easy evaluation and validation of your pump performance including statistics of pulsation with a test protocol output.
Chromatography system integration
A unique accessory driver enables integration of the flow meters to most of the leading Chromatography Data Systems (CDS), (OpenLab, Empower, LabSolutions, Clarity, WinGPC, etc). By integrating with your CDS, you can collect and document the actual flow profile of each chromatogram directly in your database. No more guesswork! The flow meter is simply added as a detector enabled by an additional RC.net/ICF protocol.
TECHNICAL DATA
| Micro Flow AB-40008 | HPLC FLOW AB-40010 | Prep Flow AB-40040 | High Flow AB-40650 | |
|---|---|---|---|---|
| Measuring Range | 10 nl-80 uL/min | 1 uL-5 mL/min | 0.1-40mL/min | 0.1-650 mL/min |
| Maximum resolution | 1 nL/min | 1uL/min | 0.1 mL/min | 0.1 mL/min |
| Accuracy | >0.2% FSD | >0.2% FSD | >0.2% FSD | >0.2% FSD |
| Precision | >0.2% FSD | >0.2% FSD | >0.2% FSD | >0.2% FSD |
| Integration Time Factor | ||||
| Maximum Pressure | 3 MPa(435 psi) | 3 MPa(435 psi) | 1.2 MPa(174 psi) | 0.3 MPa(43 psi) |
| pH Operating Range | 1 to 11 | 1 to 11 | 1 to 11 | 1 to 11 |
| Measuring Cell Volume | 5 uL | 94 uL | 58 uL | 276 uL |
| Cell Diameter | 0.43 mm | 1.8 mm | 1.4 mm | 4 |
| Cell Length | 37 mm | 37 mm | 22 mm | 22 |
| Fluidic Connectors | Female 1/4"-28 flat bottom | Female 1/4"-28 flat bottom | Female 1/4"-28 flat bottom | 8mm Barbed end with tubing*** |
| Pressure dropD | 1 mbar | 0.12 mbar* | <4 mbar | <4 mbar |
| Sensor Module | Quartz glass (borosilicate) and PEEK | PPS, SS-316 and epoxy resin | ||
| Display | High resolution OLED display | |||
| Control | USB-powered plug-and-play software | |||
| Calibration | Validated with water. Calibrations factors included | |||
| 1. Water (validated | Yes | Yes | Yes | Yes |
| 2. Methanol | Yes | Yes | Yes | Yes |
| 3. THF | Yes | Yes | _** | _** |
| 4. Acetonitrile/water | Yes | Yes | Yes | Yes |
| *@5 mL/ml with water | ** THF is not tolerated *** Tubing type to be agreed on | |||
| Temperature range 10-50°C | ||||
Technical Notes
Additional Information
Tubing installation in Biotech Liquid Flowmeters