212-204-0075
info@pyvot.tech
2.6 μm core shell column shows only one-third of back pressure to compare with 1.7 μm fully porous column although both show almost the same efficiency. By such low back pressure, a difference of density of supercritical fluid between an inlet and an outlet of the column is reduced. Consequently,
2.6 μm core shell column performs a superior separation for SFC.
Characteristics of SunShell 2-EP
Core shell silica | |||||||||||
|
|
||||||||||
|
|
|
Comparison between SunShell 2-EP and 1.7 μm fully porous 2-EP
Figure 1: Chromatogram of the separation for he 17-
component mix using the Sun Shell 2-EP 150 x 3.0 mm column. A methanol gradient of < 2 minutes was used on the Agilent 1260 Infinity SFC system. SFC
conditions: flow rate: 4.0mL/min; outlet pressure 160
bar; column temperature 55⁰C. Gradient program: 5.0-
7.5% in 0.20 min, then 7.5-20% in 1.3 min and held at 20% for 0.2 min.
Figure 2: Chromatogram of the separation for the 17-component mix using Acquity UPC2 Viridis 2-EP 100
x 3.0 mm column. 16 of the 17 components were
resolved. A methanol gradient of < 2 minutes was
used on the Agilent 1260 Infinity SFC system. SFC
conditions: flow rate 3.5 mL/min; outlet pressure 160
bar; and column temperature 70⁰C. Gradient program:
5.0-12.5% in 1.0 min, 12.5% for 0.25 min, then 12.5-20% in 0.75 min.